Thursday, January 8, 2015


In December 2009 Javelin & Hospira gave the FDA a NDA for an injectable diclofenac. Multiple amendments,emails, and years later it was approved for mono therapy or combo therapy for moderate or severe pain in December 23, 2014. 
Post marketing studies in the 1-16 year old population will be forthcoming in the next 4-5 years. 
Source: Drugs@FDA



Slightly off topic: but here's some motivation to eat right, exercise, and diet appropriately. If one does this then you can be as good looking in your 40s as one was decades ago, and still be a cheerleader. Two women did it, and this webpage highlights one for the Saints. The other team is the Bengals whose cheerleaders are nicknamed the Ben-Gals.
Source: http://www.sportingnews.com/photos/4596747-40-year-old-nfl-cheerleader-kriste-lewis-new-orleans-saints/slide/248867

cheerleader

Two brands for Naltrexone include Depade and Revia. Considering that two months ago WHO issued guidelines for preventing overdose by lay people with naloxone it might be a good factoid to recall. Scotland's program reduced both the percentage and total opioid deaths.
Two other names to be aware of are combination products:
Embeda - morphine sulfate/naltrexone
Contrave - naltrexone and bupropion


Sources: Medscape CE on Opioids, Drug Topics articles, and a BMJ editorial. http://www.bmj.com/content/349/bmj.g6580

Naltrexone skeletal.svg

Sunday, January 4, 2015

Take your zofran before you watch this....

The UK Daily Mail has an article about a South Dakota man who climbs 1,500 feet to replace a light bulb for a TV tower. The video is on the bottom of the page or you can just click <<This link>>.* You can see his well done job as it is flashing.

http://www.dailymail.co.uk/news/article-2896320/The-vertigo-inducing-moment-daredevil-climbs-1-500-feet-change-lightbulb-atop-TV-tower-pauses-SELFIE.html

https://www.youtube.com/watch?v=f1BgzIZRfT8 = the link.