"10. Methylphenidate transdermal system (Daytrana patch) The FDA issued a safety alert about the ADHD medication Daytrana patch in late June over reports of permanent loss of skin color up to 8 inches in diameter. Although it is not physically harmful, the condition is believed to be irreversible. In fact, no signs of reversibility have been seen in the 51 related chemical leukoderma cases reported to the FDA. In most cases, the skin color loss was concentrated in the area where the patch was applied, but there have been some reports of the discoloration spreading to other parts of the body. Health care professionals are encouraged to consider alternative treatments for patients experiencing this side effect."
See more at: http://www.pharmacytimes.com/product-news/10-fda-drug-warnings-pharmacists-should-know#sthash.AaZ42AJT.dpuf
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