Thursday, January 8, 2015


In December 2009 Javelin & Hospira gave the FDA a NDA for an injectable diclofenac. Multiple amendments,emails, and years later it was approved for mono therapy or combo therapy for moderate or severe pain in December 23, 2014. 
Post marketing studies in the 1-16 year old population will be forthcoming in the next 4-5 years. 
Source: Drugs@FDA



Slightly off topic: but here's some motivation to eat right, exercise, and diet appropriately. If one does this then you can be as good looking in your 40s as one was decades ago, and still be a cheerleader. Two women did it, and this webpage highlights one for the Saints. The other team is the Bengals whose cheerleaders are nicknamed the Ben-Gals.
Source: http://www.sportingnews.com/photos/4596747-40-year-old-nfl-cheerleader-kriste-lewis-new-orleans-saints/slide/248867

cheerleader

Two brands for Naltrexone include Depade and Revia. Considering that two months ago WHO issued guidelines for preventing overdose by lay people with naloxone it might be a good factoid to recall. Scotland's program reduced both the percentage and total opioid deaths.
Two other names to be aware of are combination products:
Embeda - morphine sulfate/naltrexone
Contrave - naltrexone and bupropion


Sources: Medscape CE on Opioids, Drug Topics articles, and a BMJ editorial. http://www.bmj.com/content/349/bmj.g6580

Naltrexone skeletal.svg

Sunday, January 4, 2015

Take your zofran before you watch this....

The UK Daily Mail has an article about a South Dakota man who climbs 1,500 feet to replace a light bulb for a TV tower. The video is on the bottom of the page or you can just click <<This link>>.* You can see his well done job as it is flashing.

http://www.dailymail.co.uk/news/article-2896320/The-vertigo-inducing-moment-daredevil-climbs-1-500-feet-change-lightbulb-atop-TV-tower-pauses-SELFIE.html

https://www.youtube.com/watch?v=f1BgzIZRfT8 = the link.

Tuesday, December 16, 2014


While new Hepatitis drugs are very expensive, the FDA now gives US blood banks a tool (a blood cleaning device) so that plasma may be transferred between people and not spread hepatitis, nor West nile. it is called the Intercept Blood system. It uses amotosalen (a synthetic psoralen) and UV light. After 704 people successfully used it, it passed muster.


Source: fda


Monday, December 15, 2014

To all future parents:

According to the 2012 edition of Volume 62, Number 9 of the CDC's "National Vital Statistics Reports" 3,952,841 people were born that year. Of those, 40-100 get an undesirable disease called  Severe Combined Immunodeficiency (SCID) yearly. Why is this relevant? Because if it is not detected the baby's lack of an immune system may result in death. 

This is where a Finish-American company comes in to improve life for babies. There product was able to find 17 positive cases and 6,383 negative cases out of 6,400 cases. It cannot detects related types of immunodeficiency: DiGeorge Syndrome, Omenn Syndrome, leaky-SCID or variant SCID.


It takes a few drops of blood from the baby's pes (trotter, tootsiesdogsboats, or foot) to help count the number of T Cells
The number of births daily is estimated to be 10,829 a day. Hopefully the machine will be printing out 10,829 negative results.

Sunday, December 7, 2014

According to an October article in Forbes the color of a pill may help patients think the pill works. They cited food coloring and made a comparison with salmon color and the type normally purchased. Reminds me of annatto food coloring in cheese. Incidentally that comes from this fruit. Though, it's supposed to be orange or yellow. So much for Wikipedia... though they would say don't look at the red seeds, it really is orange.
     Anyone want to think about the color is the blue and black dress that to some looked white and gold? 
wired.com/2015/02/science-one-agrees-color-dress
http://www.cnn.com/2015/02/26/us/blue-black-white-gold-dress/index.html
File:Bixa orellana fruit open.jpg
http://www.forbes.com/sites/sap/2014/10/22/the-shocking-truth-about-the-influence-of-colors/?sr_source=lift_outbrain