From Dictionary.com
From univadis:
"A recent study in patients with metastatic prostate cancer found an association between statin use and delay in time to progression to castrate-resistant prostate cancer (CRPC)
Mean patient age: 67.1±9.1 years; mean follow-up: 52 months; mean baseline prostate-specific antigen (PSA) level: 537 ng/mLSignificant difference in time to progression to CRPC: 22.7 months in non-statin users vs 30.5 months in statin users (P=.032)No significant difference in blood cholesterol and initial PSA levels according to time to progression to CRPC (P=.288, P=.198)Multivariate analysis: significantly increased odds ratio of longer time to progress to CRPC in those not having diabetes (P=.037) and those using a statin (P=.045)
Retrospective analysis of 171 patients with metastatic prostate cancer at the time of diagnosis who were treated with ADT between January 1997 and December 2013
Jung J, Lee C, Lee C, Kwon T, You D, Jeong IG, Hong JH, Ahn H, Kim CS.
Effects of statin use on the response duration to androgen deprivation therapy in metastatic prostate cancer.
Korean J Urol. 2015 Sep;56(9):630-6. doi: 10.4111/kju.2015.56.9.630. Epub 2015 Sep 2."
From univadis:
"A recent study in patients with metastatic prostate cancer found an association between statin use and delay in time to progression to castrate-resistant prostate cancer (CRPC)
Mean patient age: 67.1±9.1 years; mean follow-up: 52 months; mean baseline prostate-specific antigen (PSA) level: 537 ng/mLSignificant difference in time to progression to CRPC: 22.7 months in non-statin users vs 30.5 months in statin users (P=.032)No significant difference in blood cholesterol and initial PSA levels according to time to progression to CRPC (P=.288, P=.198)Multivariate analysis: significantly increased odds ratio of longer time to progress to CRPC in those not having diabetes (P=.037) and those using a statin (P=.045)
Retrospective analysis of 171 patients with metastatic prostate cancer at the time of diagnosis who were treated with ADT between January 1997 and December 2013
Jung J, Lee C, Lee C, Kwon T, You D, Jeong IG, Hong JH, Ahn H, Kim CS.
Effects of statin use on the response duration to androgen deprivation therapy in metastatic prostate cancer.
Korean J Urol. 2015 Sep;56(9):630-6. doi: 10.4111/kju.2015.56.9.630. Epub 2015 Sep 2."
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